Description
BPC-157 is a synthetic linear pentadecapeptide with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, produced by solid-phase peptide synthesis. It carries no terminal modifications.
The sequence is proline-rich, with three consecutive proline residues at positions 3 through 5 and additional prolines at positions 8 and 11. This composition constrains backbone flexibility and is the basis for its reported stability in acidic aqueous media relative to comparable unmodified peptides. The sequence corresponds to a fragment of a larger protein originally described in gastric juice, from which the historical “body protection compound” designation derives.
This material is supplied as a characterized reference compound for non-clinical laboratory work, such as analytical method development for proline-rich peptides, comparative stability studies across pH ranges, conformational analysis by circular dichroism, and in vitro assay development.
Chemical Information
- Sequence: GEPPPGKPADDAGLV (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val)
- Molecular Formula: C₆₂H₉₈N₁₆O₂₂
- Molecular Weight: ~1419.6 g/mol
- PubChem CID: 9941957
- CAS Number: 137525-51-0
- Physical Form: Lyophilized white powder
Storage & Handling
Store lyophilized powder at −20 °C, protected from light. Avoid moisture and repeated freeze-thaw cycles. Handle in accordance with standard laboratory safety practices.
FOR RESEARCH USE ONLY. Not for human consumption. Not intended for human or veterinary use. For laboratory research and analytical purposes only.