Description
N-Acetyl Semax Amidate is a synthetic heptapeptide analogue of Semax, which is itself based on the ACTH(4-7) fragment with a C-terminal Pro-Gly-Pro glyproline extension. This analogue carries an N-terminal acetyl group and a C-terminal amide in place of the free carboxylic acid. Both terminal modifications are standard approaches to reducing susceptibility to exopeptidase degradation.
This material is supplied as a characterized reference compound for non-clinical laboratory work, such as analytical method development for short peptides, comparative proteolytic stability studies against the unmodified sequence, and in vitro studies of ACTH-fragment and glyproline peptides.
Chemical Information
- Peptide Sequence: Ac-Met-Glu-His-Phe-Pro-Gly-Pro-NH₂
- Molecular Formula: C₃₉H₅₄N₁₀O₁₀S
- Molecular Weight: ~855.0 g/mol
- CAS Number: 2920938-90-3
- PubChem CID: 9811102
- Form: Lyophilized powder
Storage & Handling
Store at −20 °C, protected from light. Avoid moisture and repeated freeze-thaw cycles. Note that this peptide contains a methionine residue and is subject to oxidation; handle and store accordingly. Handle in accordance with standard laboratory safety practices.
FOR RESEARCH USE ONLY. Not for human consumption. Not intended for human or veterinary use. For laboratory research and analytical purposes only.